Osmosis Jones
“Every body needs a hero.”
A white blood cell policeman, with the help of a cold pill, must stop a deadly virus from destroying the human they live in, Frank.
Genres
Action, Adventure, Animation, Comedy, Family, Science Fiction
Studio
Conundrum Entertainment
Language
en
Status
Released
How Osmosis Jones performed
Budget
$75.0M
Worldwide Gross
$13.6M
Gross Profit
−$61.4M
Return
0.2× budget
Opening Wknd (est.)
$2M
Source: TMDB. Domestic/international split (~35/65, genre-typical) and the opening-weekend figure (38% of the domestic run, typical for Action) are MoviesRankd estimates. Profit is gross revenue minus production budget and excludes marketing — studios typically need ~2–2.5× budget to break even.
Where to Watch
Cast
Osmosis Jones (voice)
Chris Rock
Osmosis Jones (voice)
Thrax (voice)
Laurence Fishburne
Thrax (voice)
Drix (voice)
David Hyde Pierce
Drix (voice)
Leah (voice)
Brandy Norwood
Leah (voice)
Shane Detorre
Elena Franklin
Shane Detorre
Frank Detorre
Bill Murray
Frank Detorre
Mayor Phlegmming (voice)
William Shatner
Mayor Phlegmming (voice)
Tom Colonic (voice)
Ron Howard
Tom Colonic (voice)
Kidney Rock (voice)
Kid Rock
Kidney Rock (voice)
Mrs. Boyd
Molly Shannon
Mrs. Boyd
Bob
Chris Elliott
Bob
Officer Tom (voice)
Jonathan Adams
Officer Tom (voice)
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